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Core Science2 comprehensive topics

Pharmacology & Medication Safety

Drug classes, mechanisms of action, high-alert medication protocols, specific antidotes, and clinical nursing safety implications.

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Clinical Study Topics (2)

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Fundamental6 min read

High-Yield Clinical Antidotes & Toxicities

Rapid reference guide to life-saving antidotes, reversal agents, toxic ingestion protocols, and nursing monitoring parameters.

High-Yield Clinical Takeaways:

  • •Opioids (morphine, fentanyl, oxycodone) -> Naloxone (Narcan). Note: Naloxone half-life is shorter than most opioids; monitor for re-sedation.
  • •Warfarin (Coumadin) -> Vitamin K (Phytonadione) and Fresh Frozen Plasma (FFP) for acute bleeding.
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High-Yield8 min read

Cardiovascular Pharmacotherapy

Antihypertensives, ACE inhibitors, ARBs, Beta-Blockers, Calcium Channel Blockers, and antiarrhythmics with crucial assessment parameters.

High-Yield Clinical Takeaways:

  • •ACE inhibitors (-pril): Risk of angioedema (life-threatening airway obstruction), dry cough (switch to ARB), and hyperkalemia.
  • •Beta-Blockers (-lol): Negative inotrope and chronotrope; hold if HR < 60 bpm or SBP < 100 mmHg. Non-selective beta-blockers (propranolol) contraindicated in asthma.
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